Today's NFL Matchups

View a matchup to see picks from expert NFL handicappers.

vs

Open 4:05 pm EDT Sunday, September 21, 2025

Los Angeles is favored -1.5. Total is 45.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 4/5 (4/5 ATS)

vs

Open 4:05 pm EDT Sunday, September 21, 2025

Seattle is favored -7. Total is 42.

Last 5: 0/5 (1/5 ATS)
Last 5: 3/5 (1/5 ATS)

vs

Open 4:25 pm EDT Sunday, September 21, 2025

San Francisco is favored -1.5. Total is 44.5.

Last 5: 3/5 (3/5 ATS)
Last 5: 2/5 (2/5 ATS)

vs

Open 4:25 pm EDT Sunday, September 21, 2025

Dallas is favored -1. Total is 49.5.

Last 5: 2/5 (3/5 ATS)
Last 5: 2/5 (3/5 ATS)

vs

Open 8:20 pm EDT Sunday, September 21, 2025

Kansas City is favored -6. Total is 44.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 2/5 (3/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Atlanta is favored -4. Total is 43.5.

Last 5: 1/5 (1/5 ATS)
Last 5: 1/5 (2/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Minnesota is favored -3. Total is 43.5.

Last 5: 4/5 (2/5 ATS)
Last 5: 2/5 (2/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Green Bay is favored -7. Total is 41.

Last 5: 3/5 (3/5 ATS)
Last 5: 1/5 (1/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Jacksonville is favored -1. Total is 43.

Last 5: 2/5 (3/5 ATS)
Last 5: 2/5 (3/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Indianapolis is favored -6. Total is 43.

Last 5: 4/5 (3/5 ATS)
Last 5: 1/5 (2/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Washington is favored -1.5. Total is 44.

Last 5: 3/5 (3/5 ATS)
Last 5: 2/5 (2/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Philadelphia is favored -3.5. Total is 44.5.

Last 5: 2/5 (5/5 ATS)
Last 5: 5/5 (4/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

Tampa Bay is favored -6. Total is 42.5.

Last 5: 1/5 (2/5 ATS)
Last 5: 3/5 (2/5 ATS)

vs

Closed 1:00 pm EDT — GAME IN PROGRESS Sunday, September 21, 2025

is favored . Total is 44.

Last 5: 2/5 (2/5 ATS)
Last 5: 2/5 (2/5 ATS)

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